Clinical Guidelines

Evidence-based health information

Pain Management

Understanding and managing pain — from mild analgesia to chronic pain strategies

Pain Management

Pain is one of the most common reasons people seek medical attention or visit a pharmacy. Effective management depends on understanding the type and cause of pain and selecting the right approach — whether that is a simple painkiller, an anti-inflammatory, or a longer-term strategy for chronic pain.


Types of Pain

Pain can be acute — such as injury or post-operative pain — or chronic, lasting more than three months. Nociceptive pain arises from tissue damage and responds well to standard analgesics. Neuropathic pain results from damage to the nervous system itself and often requires different medicines such as certain antidepressants or nerve-stabilising drugs. Understanding which type of pain is present is key to choosing the right treatment.

Pain Relief Options

For mild pain, paracetamol is the safest and most widely used first choice, suitable for most people including during pregnancy. Ibuprofen and other anti-inflammatories are effective for pain with an inflammatory component but are not suitable for everyone — particularly those with stomach problems, kidney issues, or heart conditions. When pain is more severe, stronger medicines may be needed and should always be used under medical guidance for the shortest time necessary.

Living With Chronic Pain

Chronic pain affects millions of people and often cannot be fully resolved with medication alone. NICE guidelines recommend approaches such as exercise, physiotherapy, and talking therapies alongside or instead of long-term painkillers. Good sleep, pacing of activity, and psychological support play an important role in managing day-to-day life with persistent pain. A GP or pain specialist can help develop a personalised plan.

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